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A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.

Fast bowler is one wicket away from a target eight years in the making after another display of consistencyHalfway through the afternoon session, as drinks were taken after the completion of his 10th over, Mohammad Abbas waved at the Pakistan dressing room and beckoned on their p

Draw starts at 5pm BST (6pm CET)Get in touch: email John and follow us on BlueSkyHello all and welcome to live coverage of the league phase draw for this season’s Champions League. The 36 teams – 36! – will discover their various opponents, home and away and there are sure to be

While a colleague traveled along the East Coast from Canada to the Gulf of Mexico collecting oysters, Northeastern University bioinformatics graduate student Megha Prasad worked away at her computer. She zeroed in on DNA, the molecule containing instructions for making proteins t

The 80-seat venue at Edinburgh fringe combines sauna rituals with theatre, music, storytelling … and sweatTucked away behind the Summerhall arts centre is the hottest new venue at the Edinburgh fringe … quite literally. The Sauna theatre has proved popular among theatregoers at t

Entire populated areas swept away after glacial collapse causes catastrophic flood in mountainous region popular with trekkers and pilgrimsNepal-Tibet flash flood – latest updatesWhat we know so farHave you been affected by the flash floods?Nearly 1,500 people are missing, the ma

A landslide unleashed a torrent of mud and water across Nepal on Wednesday, killing at least 157 people and leaving more than 400 tourists missing near the border with China. The disaster swept away homes, roads and bridges, while officials warned the death toll could rise as res

Powerful floods in Himalayan border area sweep away houses, roads and bridgesGet our breaking news email, free app or daily news podcastDozens of Australian tourists are reportedly missing in the deadly flash floods that swept through the Nepal-Tibet border, as the Australian gov

Piketon datacenter promises to generate thousands of jobs, but environmental groups voice concern over projectOn a winding road tucked away behind forests in the Appalachian foothills of southern Ohio is where OpenAI, Nvidia and Japanese investors are set to spend $500bn on one o

Playoff second leg: Rapid 2-2 Hearts (aet, 3-4 on pens)Kara 34, Cvetkovic 119; Kabore 79, Miller 100Beau Reus made two penalty saves as heroic Hearts overcame Tomas Magnusson’s red card to pull off a stunning shootout victory away to Rapid Vienna, and book themselves a return to

Powerful floods in Himalayan border area sweep away houses, roads and bridges. Follow today’s news liveGet our breaking news email, free app or daily news podcastDozens of Australian tourists are reportedly missing in the deadly flash floods that swept through the Nepal-Tibet bor

Massive flooding near the border with Tibet killed dozens in Nepal on Wednesday. Hundreds of people were still out of contact hours after the disaster hit. A torrent of mud and debris burst from the banks of a river between China and Nepal, burying buildings and triggering a fran